The MISTIC SEAS II project "Implementation of a coherent and coordinated sub regional approach to monitoring and evaluation of marine biodiversity in Macaronesia for the second cycle of the Marine Strategy Framework Directive MSFD" is the continuation of the MISTIC SEAS.

The official start-up meeting for the project MISTIC SEAS II was held in Lisbon at the Ministry of the Sea in March 2017.

The project MISTIC SEAS worked in developing a methodology for monitoring the biodiversity descriptor in the Macaronesia sub region, focusing on the populations of three functional groups of species shared among the archipelagos of this sub region (Azores, Madeira and the Canary Islands).

MISTIC SEAS II, which was directed to the implementation of the second cycle of the Marine Strategy Framework Directive, aimed at implementing joint programs between Spain and Portugal to monitor the status of marine mammals, sea turtles and seabirds in the sub region of the Macaronesia.

MISTIC SEAS II started on March 2017 and ran until  March 2019, it had a total budget of 1.3 million euros and 80% co-financing from the European Commission. It was coordinated by the Regional Fund for Science and Technology (Regional Government of the Azores, Portugal), and had as partners the Regional Directorate of Sea Affairs, Regional Government of the Azores (Portugal); the Regional Secretary of Environment and Natural Resources, Regional Government of Madeira (Portugal); the General Directorate of Natural Resources, Safety and Maritime Services of the Ministry of the Sea of ​​Portugal; the General Directorate of Sustainability of the Coast and Sea, and the Biodiversity Foundation, both of the Ministry of Agriculture and Fisheries, Food and Environment of the Government of Spain; the General Directorate of Protection of the Natural Environment of the Government of the Canary Islands; the Regional Agency for the Development of Research and Technology and Innovation of Madeira; and the Spanish Institute of Oceanography.